Waterless coolant is commonly used in heavy over the road trucks. Its a chemical instead of a glycol blend. It does not need pressure in the cooling system to stop it from boiling.. so less stress on hoses and gaskets. It replaces the normal mix with the change of modifying the pressure cap for 0 pressure.
No substitute for cubic inches! The bore and stroke will make more power. But the details of rod length piston type etc are the devil in the details.
There is no "reniforcing" of the crank it is what it is. One advantage of the M47 crank is its a diesel crank and is a heavier forged unit, much stronger than the gas engine crank.
The other issue is youll need a 100% custom burn on the ECU to handle a stoker + bore increase with out sending things off the edge. Adding the boost in will make it even more fun...
Cheers
Dave